Mysterious Metabolic Diseases Respond to Glutathione

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This is such an interesting piece of research into glutathione I just had to blog about it:

Scientists at Stanford University School of Medicine have devised a much-needed way to monitor and find treatments for a mysterious and devastating group of metabolic diseases that arise from mutations in cells' fuel-burning mechanism.

Mitochondrial disorders can cause organ failure, seizures, stroke-like episodes and premature death. The diseases - more than three dozen in total - arise from genetic errors of the mitochondria, the cell structures that process oxygen and turn food molecules into useable energy. Mitochondrial disorders affect one in 4,000 kids and one in 8,500 adults. They are difficult to diagnose, and no treatments or cures exist.

But that could soon change. A team at Stanford and Lucile Packard Children's Hospital has discovered a biological marker they can use to monitor the diseases. The finding will enable researchers to hunt for treatments and help physicians check patients' status before health crises erupt. The research will be published online Feb. 9 in the Proceedings of the National Academy of Sciences....

The team saw that levels of glutathione, the body's primary antioxidant, were significantly reduced in white blood cells from the 20 mitochondrial disease patients in the study. The observation means patients' antioxidant defenses were indeed depleted. Glutathione was also diminished in nine patients with organic acidemias, another group of metabolic diseases that researchers think may be associated with aberrant mitochondrial function.

A second finding gave the researchers a big hint about where to hunt for treatments. Patients taking antioxidant supplements did not have depleted glutathione, they found. Scientists have long suspected antioxidants such as vitamin C and vitamin E might help patients with mitochondrial disease or organic acidemias, and doctors sometimes suggest the supplements to their patients. But no one has been able to test whether they work.

"As a clinician, one of the most frustrating things has been not being sure if supplements are doing any good," said Enns. "Now we're able to take a baseline blood reading and see 'before' and 'after' snapshots."

William Craigen, MD, PhD, the director of the metabolic clinic at Texas Children's Hospital, called this finding "the beginning of insight into the mechanisms of mitochondrial disease." Craigen, who is also medical director for the mitochondrial diagnostic lab at Baylor College of Medicine, was not involved in the Stanford study. "This new research provides an opportunity to start treating a heterogeneous group of diseases in a single fashion, with a simple and easy-to-administer treatment, potentially improving patients' long-term outcomes," he added.

Glutathione measurements could also help diagnose patients, Enns said, by giving physicians a clear indication that something is awry in the mitochondria. Genetic and molecular tests have already led to increases in the number of diagnoses, but the diagnosis is still difficult to pin down.

The method Enns' team used to measure glutathione, called high-dimensional flow cytometry, has limitations: it requires very fresh blood samples, uses expensive equipment only available in research labs, and provides relative rather than absolute glutathione measurements. Now that the team knows what metabolic change to look for, they're working to develop a more broadly applicable measurement technique.

And glutathione measurements could help scientists unravel other disease mysteries, too. "You name the disease, you can postulate mitochondrial involvement," Enns said. "It's been proposed for everything from poor vision to hearing loss, kidney disease, liver disease, autism spectrum disorders, diabetes, Alzheimer disease, cancers. Our work could lead to research on therapies for a broad range of disorders." Read the entire excerpt at Medical News Today


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My Sad News and an Apology

To all those lovely people who are subscribed to this blog, I have to apologize to you for leaving you hanging with little or no explanation.

We have had a tragedy in my family, my little grandson was lost to a severe congenital heart defect and I just left everything I was doing, and spent time with my beautiful son who was having a great deal of trouble handling his sadness over the loss of his first child.

I am back now, though and will begin to update the blog again more regularly, now that things are getting back to normal in my life again.

I have to tell you, that if it had not been for taking MaxGXL every day twice a day, I am not at all sure I would have had the strength needed to keep going through this difficult time. I never want to find out what life would be like without it as now I know the Max has helped me and my family find the inner and outer strength all through the many trips back and forth from hospitals over 100km away, the arrangements for the cremation and service for our little boy and the many trips to hold my son and his wife while they cried their grief.

thank you all for your understanding at this time, Annie

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How to Choose a Network Marketing Company

Image by alchymy8 via FlickrNetwork Marketing companies seem to spring up like mushrooms, so how do you choose between them, what do you look for to give you the best chance of success?

Here's my list of criteria:

• Find a product and service you are passionate about (nothing less)
• Be sure the company has a continuity of sales ensuring you a residual income
• Look for great support in your team
• Look for a generous compensation plan with a fair distribution of profits
• Check out their track record, like any company you will need to to your due diligence e.g. if they are a new company do your research on the founders, partners and managers.
  
• Look for a good system that's easy to understand and follow

I have joined a few Networks in my time and some I learned the most from were the ones that failed, I learned what to look for and what hype to ignore. Max International ticks even more boxes for me than on the list above.

Adding to that list in Max International I found:

• a product that was originally formulated by a world class doctor of medicine
• tests on all products has and will continue to be rigorous and up to medical standards
• Formulas are being patented with the same patents usually reserved for medical drugs
• amazing people including more doctors are being attracted on board
  

With this kind of continual growth and the company is only just over 12 months old it can go no-where but UP!



Max Your Life!

For more information go to: Living Life To The Max

My Max International Sponsor ID is 129056 please use it when you join up as a Preferred Customer (retail customer or Associate (discount customer). Thankyou!

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MaxGXL: A Message From Steve Scott

May 2008
MAX INTERNATIONAL ASSOCIATE NEWSLETTER
By Steve Scott: Science to the Max!

"For 32 years I’ve made my living by finding breakthrough products, acquiring their marketing rights, and selling those products to tens of millions of families in America and throughout the world. My partners and I have been able to do this over and over again, building a number of businesses that have achieved billions of dollars in sales.

In 2006, I found what I considered the biggest “breakthrough product” of my career. I was convinced it was a breakthrough, not because of a ‘gut-feel’ or a hope, but because the product was a true scientific breakthrough. We ultimately named this product MaxGXL. Its development was based upon the scientific research and development of one of the world’s great medical researchers, Dr. Robert H. Keller.

Throughout my career I’ve had the chance to work closely with a number of world-renowned experts and even a few geniuses. For example, I had the privilege of working with Dr. Alf Nachemson, who was called “the father of modern back surgery, and the world’s greatest living expert on the human spine,” by the president of Harvard Medical School. I’ve worked with a number of the world’s leading nutritional experts, including Dr. Oliver Alabaster (head of disease prevention at George Washington University) and Dr. Barry Sears (creator of the “Zone” approach to dieting).

But of all the experts I have ever known, of all the geniuses I have ever interacted with, no one has ever “wowed” me like Dr. Keller. In my opinion, he is truly in a league all by himself. His 29-page curriculum vitae only reflects “the tip of the iceberg,” of this man’s knowledge and accomplishments.

But as impressive as Dr. Keller and his research were, he and his research were not the basis of my excitement or ultimate commitment. What truly amazed me was what his product accomplished at a cellular level, and the fact that the degree of what it accomplished at a cellular level could be verified and quantified through a sophisticated blood test. These tests demonstrated that MaxGXL could substantially increase cellular production of glutathione, one of the body’s most important proteins (a tri-peptide).

Thousands of medical studies had identified the incredible roles this “miracle protein” plays in every cell’s health, and the ultimate health of a person. Studies had also shown that the body’s production of glutathione decreased by 8 to 12 percent per decade, accelerating aging and making the body more vulnerable to the various diseases of aging. Dr. Keller was able to show me “before and after” blood tests of his various patients who had taken MaxGXL. After only 60 days, they had experienced an extraordinary rise in their glutathione levels.

But this was not the end of the story. I started taking a few capsules a day and quickly noticed that my energy level wasn’t falling off of a cliff in the afternoons. Instead, I felt energetic, mentally alert and just plain “great” from the time I woke up until the time I’d go to bed. My partners and I began handing out sample bottles to friends and they quickly reported the same kind of results and even more astounding results—so much so that almost none of them wanted to go a single day without the product.I not only realized this was a “breakthrough product,” but that it was also an incredible business opportunity. Although I’ve marketed dozens of breatkthrough products, I’ve never sold any product that created a customer frenzy and a product loyalty like this one was creating. That was all I needed to commit my mind and resources to this newest and most exciting venture.

But then something happened that changed the course of my life. I gave the product to my assistant’s husband with the hope of improving his energy level. It did much more than that. Within a matter of weeks, Kenny’s quality of life was radically changed for the better. The change was so astounding, it left everyone who knew him (including his doctors) scratching their heads. Kenny’s transformation changed my attitude about this product in a very overpowering way. What was the most exciting business opportunity of my life became a life-altering mission. You see, Kenny had all but given up on life. All I could think about was how many more Kennys were out there. I felt a compulsion that I had to do EVERYTHING and ANYTHING I could to get the product into millions of homes throughout the world.

I called my partners at American Telecast and told them that I was retiring. ATC had been my business home for 31 years. My partners were closer than brothers. We had been together through thick and thin for three decades. We had created billions of dollars in sales together and had each made tens of millions in personal income. And yet, my decision was an easy one. In terms of seeking a breakthrough product that had the potential of changing millions of lives, MaxGXL was such a product.

MaxGXL will always be the cornerstone product of our company. But it will not be our only product. Dr. Keller and the Max Management team are pursuing other science-based (and scientifically proveable) products. We are currently working together with additional esteemed scientists to develop breakthrough products that can make a demonstrably significant difference in the health and quality of the lives of our Associates and Preferred Customers."

Steve Scott


Max Your Life!

For more information go to: Living Life To The Max

My Max International Sponsor ID is 129056 please use it when you join up as a Preferred Customer (retail customer or Associate (discount customer). Thankyou!

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Boost Your Metabolism with Superoxide Dismutase

Taking MaxGXL and Max N-Fuse together could change your life!

Researchers have found that Superoxide Dismutase or SOD for short rapidly converts fat into usable energy, thus turbo-charging metabolism.

MnSOD or (manganese dependent SOD) is also now known to be a primary protector of the thyroid hormone. This enzyme naturally rises as thyroid hormone activity is increased, acting as a protective buffer to support increased metabolic rate. If this enzyme, or the selenium-dependent GSH (glutathione) are lacking, then activation of thyroid hormone generates friction and stress in the form of excessive free radicals. This results in wear and tear to the thyroid gland, liver, and nerves.* A lack of manganese is clearly associates with reduced function of thyroid hormone in the body.*

A lack of thyroid hormone slows your metabolism leading the way for you to develop Metabolic Syndrome and all its associated health risks: obesity, diabetes, heart disease, accelerated aging, etc...

New research has shown that as free radical stress increases, due to lacking GSH and MnSOD activity, fat begins to accumulate in the liver, generating further free radical stress in the form of damaged fats, known as lipid peroxides. This makes a stressed metabolic situation worse. Once this happens a person is more likely to struggle with weight loss.

Recent discoveries show that this free radical issue stresses normal insulin function in the liver.. As the liver and thyroid become inefficient, the problems play off each other in a catch 22 situation.

Would you like to find out how different your life could be if your health changed this much? Go on...

Max Your Life, today!

For more information go to: Living Life To The Max

My Max International Sponsor ID is 129056 please use it when you join up as a Preferred Customer (retail customer) or Associate (discount customer). Thankyou!.

Inside Scoop: Where are Buffet, Trump and Kiyosaki Investing?

Watch this video to learn where the true investors are putting their money and what they have to say about the economy right now:

What's a 'true investor'? Someone who makes millions whether the market is going up or down.





Max Your Life!

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My Max International Sponsor ID is 129056 please use it when you join up as a Preferred Customer (retail customer or Associate (discount customer). Thankyou!

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• Don't Sell Your Product Recommend It

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My MaxGXL Success Story

I have to tell you all about my last few weeks on MaxGXL.

WOW what a difference!

I have more energy and I am losing weight without really trying, interesting thing is I'm not even on MaxWLX. I have worked out that it is because I am detoxing, as my liver and fat cells release their toxic overload the weight is just coming off.

Did you know that your body will store toxins within fat cells? It is a well known fact, and you have to be careful at times about losing weight without taking care to use a supplement that takes care of the toxins at the same time.

Because I am losing weight the 'right' way round, as a result of detoxing, I am sure the glutathione is taking care of the toxins and my weight loss is not resulting in too many nasty "released toxin' side effects. This is great news as my Mum has DDT stored in her fat cells and many doctors have told her that the repercussions of losing weight could be that if these were released she could end up with more cancer.

So far so good, Mum has also lost weight and is feeling better than ever before. More energy, more sleep and less stress and no sign of a cancer popping up. We are both so very happy that we found this supplement.

If you are in the US you can sign right up, right now to begin ordering your MaxGXL.

As for we here in Australia and NZ we only have to wait a little longer, if you are in Australia or New Zealand you can contact me for more information and for your free one weeks trial.

It will be here soon, along with the other great Max products. Big announcement any day!!! For one I can't wait to begin ordering from our Aussie base. I swore I would never get involved with a MLM again, well with the products these guys are producing, the world class doctors like Dr Keller and Dr Rosedale on board, the research, double blind studies and up and coming new products to be released I would be a fool not to get in on the act. Lucky me I got in on the ground floor in Australia, places are still left for those wishing to get in on the act.


Max Your Life!

For more information go to: Living Life To The Max

My Max International Sponsor ID is 129056 please use it when you join up as a Preferred Customer (retail customer or Associate (discount customer). Thankyou!

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